General Information of This Target
Target ID
BTDT10246
Target Name
Shaker IR potassium channel
Target Bioclass
Transporter and channel
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N.A.
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    Potassium channel toxin alpha-KTx 2.2 Dissociation constant
160 nM
[1], [2], [3], [4]
 Toxin Info    Potassium channel toxin alpha-KTx 1.1 Inhibition constant
227 nM
[5- 25]
 Toxin Info    N.vectensis toxin 4 Effect . [26]
 Toxin Info    N.vectensis toxin 5 Effect . [26]
 Toxin Info    U-scoloptoxin(15)-Sm2a Effect . [27], [28]
 Toxin Info    Venom peptide Sh41 Effect . [29]
 Toxin Info    Venom peptide Sh42 Effect . [29]
 Toxin Info    Mu-conotoxin CnIIIC Inhibition rate . [30], [31], [32]
 Toxin Info    Toxin PhcrTx2 Inhibition rate . [33]
 Toxin Info    Neurotoxic enhancer CSTX-13 Inhibition rate . [34], [35], [36], [37]
 Toxin Info    U-actitoxin-Oulsp1 Inhibition rate . [38]
 Toxin Info    Potassium channel toxin kappa-KTx 1.2 Inhibition rate . [39- 43]
 Toxin Info    Mambaquaretin-1 Inhibition rate . [44], [45], [46]
 Toxin Info    Potassium channel toxin epsilon-KTx 1.1 Inhibition rate
10 %
[47- 51]
 Toxin Info    Potassium channel toxin AbeTx1 Inhibition rate
15 %
[52]
 Toxin Info    Kappa-actitoxin-Ate1a Inhibition rate
23 %
[53]
 Toxin Info    Peptide TsPep3 Inhibition rate
27 %
[48], [49], [51]
 Toxin Info    Potassium channel toxin epsilon-KTx 1.2 Inhibition rate
27 %
[49], [48], [50], [51]
 Toxin Info    Potassium channel toxin alpha-KTx 21.1 Inhibition rate
30 %
[47- 56]
 Toxin Info    Potassium channel toxin alpha-KTx 8.6 Inhibition rate
70 %
[57], [58]
 Toxin Info    Mesomartoxin IC50
0.054 nM
[59]
 Toxin Info    Kunitz-type conkunitzin-S1 IC50
1.33 nM
[60], [61], [62]
References
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Ref 31 Large-scale discovery of conopeptides and conoproteins in the injectable venom of a fish-hunting cone snail using a combined proteomic and transcriptomic approach. J Proteomics. 2012 Sep 18;75(17):5215-25. doi: 10.1016/j.jprot.2012.06.001. Epub 2012 Jun 13.
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Ref 47 Proteomic endorsed transcriptomic profiles of venom glands from Tityus obscurus and T. serrulatus scorpions. PLoS One. 2018 Mar 21;13(3):e0193739. doi: 10.1371/journal.pone.0193739. eCollection 2018.
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Ref 60 Production of recombinant Conkunitzin-S1 in Escherichia coli. Protein Expr Purif. 2006 Jun;47(2):640-4. doi: 10.1016/j.pep.2006.01.019. Epub 2006 Feb 20.
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