Peptide Information

General Information of This Peptide
Peptide ID
BTDP005217
Peptide Name
U-scoloptoxin(15)-Sm2a
Symonym
U-SLPTX(15)-Sm2a
Species
Scolopendra morsitans (Tanzanian blue ringleg centipede)
Uniprot Name
TXF2A_SCOMO
Alphafold ID
P0DPT5
3D Structure
Download
2D Sequence
3D Structure
Source
RSCB PDB: 6BL9
Sequence
MKFYIVFCLFVVLLINFAAAEETEEPIRHAKKNPSEGECKKACADAFANGDQSKIAKAEN
FKDYYCNCHIIIH
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Sequence Length
73
Mass (Da)
8302
Signal Sequence
MKFYIVFCLFVVLLINFAAA
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Sequence Removed Signal Peptide
EETEEPIRHAKKNPSEGECKKACADAFANGDQSKIAKAENFKDYYCNCHIIIH
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Disulfide Bond
39-66;43-68
PDB ID
6BL9
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Chilopoda
Order: Scolopendromorpha
Family: Scolopendridae
Genus: Scolopendra
Species: Scolopendra morsitans
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.1 Effect .
10 μM
 . [1], [2]
 Target Info    Kv1.2 Effect .
10 μM
 . [1], [2]
 Target Info    Kv1.3 Effect .
10 μM
 . [1], [2]
 Target Info    Kv1.4 Effect .
10 μM
 . [1], [2]
 Target Info    Kv1.5 Effect .
10 μM
 . [1], [2]
 Target Info    Kv1.6 Effect .
10 μM
 . [1], [2]
 Target Info    Kv2.1 Effect .
10 μM
 . [1], [2]
 Target Info    Kv3.1 Effect .
10 μM
 . [1], [2]
 Target Info    Kv4.2 Effect .
10 μM
 . [1], [2]
 Target Info    Kv11.1 Effect .
10 μM
 . [1], [2]
 Target Info    Kv11.1 Effect .
10 μM
 . [1], [2]
 Target Info    Kv7.1 Effect .
10 μM
 . [1], [2]
 Target Info    Kv7.2 Effect .
10 μM
 . [1], [2]
 Target Info    Kv7.4 Effect .
10 μM
 . [1], [2]
 Target Info    Kv7.5 Effect .
10 μM
 . [1], [2]
 Target Info    Shaker-IR Effect .
10 μM
 . [1], [2]
References
Ref 1 Clawing through evolution: toxin diversification and convergence in the ancient lineage Chilopoda (centipedes). Mol Biol Evol. 2014 Aug;31(8):2124-48. doi: 10.1093/molbev/msu162. Epub 2014 May 20.
Ref 2 A Centipede Toxin Family Defines an Ancient Class of CS Defensins. Structure. 2019 Feb 5;27(2):315-326.e7. doi: 10.1016/j.str.2018.10.022. Epub 2018 Dec 13.
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