Target Information

General Information of This Target
Target ID
BTDT10025
Target Name
Calcium-activated potassium channel subunit alpha-1
Target Bioclass
Transporter and channel
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N.A.
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    IbTx (D19C) . . [1]
 Toxin Info    IbTx . . [2]
 Toxin Info    Potassium channel toxin alpha-KTx 2.1 Dissociation constant
>25 nM
 [3], [4], [5], [6]
 Toxin Info    Potassium channel toxin alpha-KTx 1.2 Dissociation constant
43 nM
 [7], [8], [9], [10]
 Toxin Info    Hemitoxin Dissociation constant
20 μM
 [11]
 Toxin Info    IbTx (D4N,S10A) Inhibition constant
0.02 nM
 [12]
 Toxin Info    IbTx (D4N,D6N,S10A,D19N,D24N) Inhibition constant
0.027 nM
 [12]
 Toxin Info    IbTx (S10A) Inhibition constant
0.13 nM
 [12]
 Toxin Info    IbTx (S10A,D24N) Inhibition constant
0.15 nM
 [12]
 Toxin Info    Potassium channel toxin alpha-KTx 1.3 Inhibition constant
0.25 nM
 [13]
 Toxin Info    IbTx (S10A,G30N) Inhibition constant
0.37 nM
 [12]
 Toxin Info    IbTx (D4N,D6N,S10A) Inhibition constant
7 nM
 [12]
 Toxin Info    Potassium channel toxin alpha-KTx 3.1 Inhibition constant
1.56 μM
 [5- 20]
 Toxin Info    Conotoxin im23b Effect . [21], [22]
 Toxin Info    Toxin II.11 (A25) Inhibition rate . [11]
 Toxin Info    Toxin II.11 (A25R) Inhibition rate . [11]
 Toxin Info    Toxin II.11 (P10S) Inhibition rate . [11]
 Toxin Info    Toxin II.11 (S14W) Inhibition rate . [11]
 Toxin Info    Potassium channel toxin alpha-KTx 2.1 Inhibition rate . [3], [4], [6]
 Toxin Info    Potassium channel toxin alpha-KTx 1.6 IC50
0.3 nM
 [23- 46]
 Toxin Info    Potassium channel toxin alpha-KTx 1.5 IC50
0.65 nM
 [23- 47]
 Toxin Info    Potassium channel toxin alpha-KTx 1.1 IC50
5.9 nM
 [5- 63]
References
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