Peptide Information

General Information of This Peptide
Peptide ID
BTDP008776
Peptide Name
IbTx (D19C)
Symonym
IbTx (D19C)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
QFTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ
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Mutant Sequence
QFTDVDCSVSKECWSVCKCLFGVDRGKCMGKKCRCYQ
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Sequence Length
37
Mass(Da)
4354
Sequence Removed Signal Peptide
QFTDVDCSVSKECWSVCKCLFGVDRGKCMGKKCRCYQ
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    KCa1.1 . . .
Blocker
 [1]
 Target Info    KCa Dissociation constant
0.022 nM
 .
Blocker
 [2]
References
Ref 1 Localization and developmental expression of BK channels in mammalian cochlear hair cells. Neuroscience. 2005;130(2):475-84. doi: 10.1016/j.neuroscience.2004.09.038.
Ref 2 Distribution of high-conductance Ca(2+)-activated K+ channels in rat brain: targeting to axons and nerve terminals. J Neurosci. 1996 Feb 1;16(3):955-63. doi: 10.1523/JNEUROSCI.16-03-00955.1996.
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