Peptide Information

General Information of This Peptide
Peptide ID
BTDP008376
Peptide Name
Kappa-actitoxin-Bcs3b
Symonym
Potassium channel toxin BcsTx2
Species
Bunodosoma caissarum (Sea anemone)
Uniprot Name
K1B2_BUNCI
Alphafold ID
C0HJC3
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: C0HJC3
Sequence
ACKDGFPTATCQHAKLVGNCKNSQKYRANCAKTCGPC
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Sequence Length
37
Mass (Da)
3919
Sequence Removed Signal Peptide
ACKDGFPTATCQHAKLVGNCKNSQKYRANCAKTCGPC
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Disulfide Bond
2-37;11-30;20-34
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Kingdom: Metazoa
Phylum: Cnidaria
Class: Anthozoa
Order: Actiniaria
Family: Actiniidae
Genus: Bunodosoma
Species: Bunodosoma caissarum
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.4 Inhibition rate .
3 μM
Blocker
 [1]
 Target Info    Kv2.1 Inhibition rate .
3 μM
Blocker
 [1]
 Target Info    Kv1.5 Inhibition rate .
3 μM
Blocker
 [1]
 Target Info    Kv4.1 Inhibition rate .
3 μM
Blocker
 [1]
 Target Info    Kv4.3 Inhibition rate .
3 μM
Blocker
 [1]
 Target Info    Kv11 Inhibition rate .
3 μM
Blocker
 [1]
 Target Info    Kv4.2 Inhibition rate .
3 μM
Blocker
 [1]
 Target Info    Kv1.6 IC50
7.76 nM
 .
Blocker
 [1]
 Target Info    Kv1.6 IC50
7.76 nM
 .
Blocker
 [1]
 Target Info    Kv1.3 IC50
13.12 nM
 .
Blocker
 [1]
 Target Info    Kv1.3 IC50
13.12 nM
 .
Blocker
 [1]
 Target Info    Kv1 IC50
14.42 nM
 .
Blocker
 [1]
 Target Info    Kv1 IC50
14.42 nM
 .
Blocker
 [1]
 Target Info    Shaker-IR IC50
49.14 nM
 .
Blocker
 [1]
 Target Info    Kv1.2 IC50
80.4 nM
 .
Blocker
 [1]
 Target Info    Kv1.2 IC50
80.4 nM
 .
Blocker
 [1]
References
Ref 1 Biochemical and electrophysiological characterization of two sea anemone type 1 potassium toxins from a geographically distant population of Bunodosoma caissarum. Mar Drugs. 2013 Mar 6;11(3):655-79. doi: 10.3390/md11030655.
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