Peptide Information

General Information of This Peptide
Peptide ID
BTDP005347
Peptide Name
Beta-toxin Tf1a
Species
Tityus fasciolatus (Central Brazilian scorpion)
Uniprot Name
SCX1A_TITFA
Alphafold ID
P0DQH5
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: P0DQH5
Sequence
MKGMILFISCLLLIGIVVECKEGYLMDHEGCKLSCFIRPSGYCGSECKIKKGSSGYCAWP
ACYCYGLPNWVKVWERATNRCGKK
   Click to Show/Hide
Sequence Length
84
Mass (Da)
9426
Signal Sequence
MKGMILFISCLLLIGIVVEC
   Click to Show/Hide
Sequence Removed Signal Peptide
KEGYLMDHEGCKLSCFIRPSGYCGSECKIKKGSSGYCAWPACYCYGLPNWVKVWERATNR
CGKK
   Click to Show/Hide
Disulfide Bond
31-81;35-57;43-62;47-64
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Tityus
Species: Tityus fasciolatus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    BgNav1 Inhibition rate .
100 nM
 . [1]
 Target Info    VdNav Inhibition rate .
100 nM
 . [1]
 Target Info    Nav1.1 Inhibition rate
17 - 30 %
100 nM
 . [1]
 Target Info    Nav1.2 Inhibition rate
17 - 30 %
100 nM
 . [1]
 Target Info    Nav1.3 Inhibition rate
17 - 30 %
100 nM
 . [1]
 Target Info    Nav1.6 Inhibition rate
17 - 30 %
100 nM
 . [1]
 Target Info    Nav1.7 Inhibition rate
17 - 30 %
100 nM
 . [1]
 Target Info    Nav1.4 Inhibition rate
53 %
100 nM
 . [1]
 Target Info    Nav1.5 Inhibition rate
71 %
100 nM
 . [1]
References
Ref 1 Subtype Specificity of -Toxin Tf1a from Tityus fasciolatus in Voltage Gated Sodium Channels. Toxins (Basel). 2018 Aug 22;10(9):339. doi: 10.3390/toxins10090339.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.