Target Information

General Information of This Target
Target ID
BTDT200041
Target Name
Varroa destructor voltage-gated sodium channel
Target Bioclass
Transporter and channel
Taxonomy ID
109461
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Mesostigmata
Family: Varroidae
Genus: Varroa
Species: Varroa destructor
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    Beta-toxin Tf1a Inhibition rate . [1]
 Toxin Info    Beta/kappa-theraphotoxin-Gi1a IC50
124.05 nM
 [2]
References
Ref 1 Subtype Specificity of -Toxin Tf1a from Tityus fasciolatus in Voltage Gated Sodium Channels. Toxins (Basel). 2018 Aug 22;10(9):339. doi: 10.3390/toxins10090339.
Ref 2 GiTx1(/-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. 2020 Sep;176:138-149. doi: 10.1016/j.biochi.2020.07.008. Epub 2020 Jul 24.
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