Peptide Information

General Information of This Peptide
Peptide ID
BTDP008788
Peptide Name
BmK86-P1
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
ACSKPCRKYCIDKGARNGKCINGRCHCYY
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Sequence Length
29
Mass (Da)
3306
Sequence Removed Signal Peptide
ACSKPCRKYCIDKGARNGKCINGRCHCYY
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Disulfide Bond
2-20;6-25;10-27
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv4.1 Inhibition rate
3 %
1 μM
Blocker
 [1]
 Target Info    Kv1.1 Inhibition rate
4 %
1 μM
Blocker
 [1]
 Target Info    Kv3.2 Inhibition rate
4 %
1 μM
Blocker
 [1]
 Target Info    Kv4.3 Inhibition rate
5 %
1 μM
Blocker
 [1]
 Target Info    Kv1.6 Inhibition rate
11 %
1 μM
Blocker
 [1]
 Target Info    Kv4.2 Inhibition rate
11 %
1 μM
Blocker
 [1]
 Target Info    Kv11 Inhibition rate
13 %
1 μM
Blocker
 [1]
 Target Info    Kv1.3 Inhibition rate
52 %
1 μM
Blocker
 [1]
 Target Info    Kv1.2 IC50
28.5 nM
 .
Blocker
 [1]
References
Ref 1 BmK86-P1, a New Degradation Peptide with Desirable Thermostability and Kv1.2 Channel-Specific Activity from Traditional Chinese Scorpion Medicinal Material. Toxins (Basel). 2021 Aug 30;13(9):610. doi: 10.3390/toxins13090610.
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