Peptide Information

General Information of This Peptide
Peptide ID
BTDP004951
Peptide Name
Beta-theraphotoxin-Cd1a
Symonym
Beta-TRTX-Cd1a
Species
Ceratogyrus darlingi (Rear horned baboon tarantula)
Uniprot Name
TX1_CERDA
Alphafold ID
P0DL84
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: P0DL84
Sequence
DCLGWFKSCDPKNDKCCKNYSCSRRDRWCKYDL
   Click to Show/Hide
Sequence Length
33
Mass (Da)
4038
Sequence Removed Signal Peptide
DCLGWFKSCDPKNDKCCKNYSCSRRDRWCKYDL
   Click to Show/Hide
Disulfide Bond
2-17;9-22;16-29
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Theraphosidae
Genus: Ceratogyrus
Species: Ceratogyrus darlingi
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
16 nM
 . . [1]
 Target Info    Nav1.3 IC50
>30 μM
 . . [1]
 Target Info    Nav1.4 IC50
>30 μM
 . . [1]
 Target Info    Nav1.5 IC50
>30 μM
 . . [1]
 Target Info    Nav1.6 IC50
>30 μM
 . . [1]
 Target Info    Cav1.3 IC50
>30 μM
 . . [1]
 Target Info    Cav3.1 IC50
>30 μM
 . . [1]
 Target Info    Cav2.2 IC50
˜3 μM
 . . [1]
 Target Info    Cav2.2 IC50
˜3 μM
 . . [1]
 Target Info    Nav1.2 IC50
0.13 μM
 . . [1]
 Target Info    Nav1.1 IC50
2.18 μM
 . . [1]
 Target Info    Nav1.7 IC50
3.34 μM
 . . [1]
 Target Info    Nav1.8 IC50
6.92 μM
 . . [1]
References
Ref 1 Discovery and mode of action of a novel analgesic -toxin from the African spider Ceratogyrus darlingi. PLoS One. 2017 Sep 7;12(9):e0182848. doi: 10.1371/journal.pone.0182848. eCollection 2017.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.