Peptide Information

General Information of This Peptide
Peptide ID
BTDP008494
Peptide Name
Potassium channel toxin alpha-KTx 3.13
Symonym
MeuKTx
Species
Mesobuthus eupeus (Lesser Asian scorpion) (Buthus eupeus)
Uniprot Name
KAX3D_MESEU
Alphafold ID
P86396
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P86396
Sequence
VGINVKCKHSGQCLKPCKDAGMRFGKCMNGKCDCTPK
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Sequence Length
37
Mass (Da)
3987
Sequence Removed Signal Peptide
VGINVKCKHSGQCLKPCKDAGMRFGKCMNGKCDCTPK
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Disulfide Bond
7-27;13-32;17-34
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Mesobuthus
Species: Mesobuthus eupeus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.4 Inhibition rate .
2 μM
Blocker
 [1]
 Target Info    Kv1.5 Inhibition rate .
2 μM
Blocker
 [1]
 Target Info    Kv3.1 Inhibition rate .
2 μM
Blocker
 [1]
 Target Info    Kv11 Inhibition rate .
2 μM
Blocker
 [1]
 Target Info    Kv4.3 Inhibition rate .
2 μM
Blocker
 [1]
 Target Info    Shaker-IR Inhibition rate
19 %
2 μM
Blocker
 [1]
 Target Info    Kv1.6 Inhibition rate
93 %
2 μM
Blocker
 [1]
 Target Info    Kv1.3 IC50
171 pM
 .
Blocker
 [1]
 Target Info    Kv1 IC50
203.15 pM
 .
Blocker
 [1]
 Target Info    Kv1.3 IC50
0.171 nM
 .
Blocker
 [1]
 Target Info    Kv1 IC50
0.203 nM
 .
Blocker
 [1]
 Target Info    Kv1.2 IC50
8.92 nM
 .
Blocker
 [1]
 Target Info    Kv1.2 IC50
8.92 nM
 .
Blocker
 [1]
References
Ref 1 A potent potassium channel blocker from Mesobuthus eupeus scorpion venom. Biochimie. 2010 Dec;92(12):1847-53. doi: 10.1016/j.biochi.2010.08.003. Epub 2010 Aug 14.
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