Peptide Information

General Information of This Peptide
Peptide ID
BTDP003501
Peptide Name
Toxin Acra3
Species
Androctonus crassicauda (Arabian fat-tailed scorpion)
Uniprot Name
TX30_ANDCR
Alphafold ID
E7BLC7
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: E7BLC7
Sequence
MKIIFLVLMMILSEVYSDRDGYPVHDGTNCKYSCDIREKWEYCTPLCKRRNAKTGYCYAF
ACWCIGLPDEVKVYGDDGIFCKSG
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Sequence Length
84
Mass (Da)
9698
Signal Sequence
MKIIFLVLMMILSEVYS
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Sequence Removed Signal Peptide
DRDGYPVHDGTNCKYSCDIREKWEYCTPLCKRRNAKTGYCYAFACWCIGLPDEVKVYGDD
GIFCKSG
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Disulfide Bond
30-81;34-57;43-62;47-64
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Androctonus
Species: Androctonus crassicauda
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.1 Inhibition rate . . . [1], [2]
 Target Info    Nav1.2 Inhibition rate . . . [1], [2]
 Target Info    Nav1.3 Inhibition rate . . . [1], [2]
 Target Info    Nav1.4 Inhibition rate . . . [1], [2]
 Target Info    Nav1.5 Inhibition rate . . . [1], [2]
 Target Info    Nav1.6 Inhibition rate . . . [1], [2]
References
Ref 1 Purification and cDNA cloning of a novel neurotoxic peptide (Acra3) from the scorpion Androctonus crassicauda. Peptides. 2012 Sep;37(1):106-12. doi: 10.1016/j.peptides.2012.07.009. Epub 2012 Jul 20.
Ref 2 Biological assays on the effects of Acra3 peptide from Turkish scorpion Androctonus crassicauda venom on a mouse brain tumor cell line (BC3H1) and production of specific monoclonal antibodies. Toxicon. 2013 Dec 15;76:350-61. doi: 10.1016/j.toxicon.2013.09.009. Epub 2013 Sep 19.
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