Peptide Information

General Information of This Peptide
Peptide ID
BTDP001694
Peptide Name
U-actitoxin-Oulsp2
Symonym
OspTx2b
Species
Oulactis sp. (Sea anemone)
Uniprot Name
K1B2_OULSP
Alphafold ID
A0A330KUG5
3D Structure
Download
2D Sequence
3D Structure
Source
RSCB PDB: 6BUC
Sequence
MNTKLVVVFLLSAILFVSVTASRPGKDLERDEAYETYDDERPYFKRACKDNLPAATCSNV
KANNNCSSEKYKTNCAKTCGEC
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Sequence Length
82
Mass (Da)
9151
Signal Sequence
MNTKLVVVFLLSAILFVSVTA
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Sequence Removed Signal Peptide
SRPGKDLERDEAYETYDDERPYFKRACKDNLPAATCSNVKANNNCSSEKYKTNCAKTCGE
C
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Disulfide Bond
48-82;57-75;66-79
PDB ID
6BUC
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Kingdom: Metazoa
Phylum: Cnidaria
Class: Anthozoa
Order: Actiniaria
Family: Actiniidae
Genus: Oulactis
Species: Oulactis sp. MM-2018
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    KCa3.1 Inhibition rate .
100 nM
 . [1]
 Target Info    Kv1.1 Inhibition rate .
100 nM
 . [1]
 Target Info    Kv1.3 Inhibition rate .
100 nM
 . [1]
 Target Info    KvAP Inhibition rate .
100 nM
 . [1]
 Target Info    Kv1.2 Inhibition rate .
100 nM
 . [1]
 Target Info    Nav1.4 Inhibition rate .
100 nM
 . [1]
 Target Info    Kv11 Inhibition rate .
100 nM
 . [1]
 Target Info    KCa1.1 Inhibition rate .
100 nM
 . [1]
References
Ref 1 Synthesis, folding, structure and activity of a predicted peptide from the sea anemone Oulactis sp. with an ShKT fold. Toxicon. 2018 Aug;150:50-59. doi: 10.1016/j.toxicon.2018.05.006. Epub 2018 May 19.
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