Peptide Information

General Information of This Peptide
Peptide ID
BTDP000576
Peptide Name
Potassium channel toxin ShK (C3[Abu],C39[Abu])
Symonym
Potassium channel toxin ShK (C3[Abu],C39[Abu])
3D Structure
Original Sequence
RSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC
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Mutant Sequence
RS[Abu]IDTIPKSRCTAFQCKHSMKYRLSFCRKTCGT[Abu]
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Sequence Length
35
Mass(Da)
4021
Sequence Removed Signal Peptide
RS[Abu]IDTIPKSRCTAFQCKHSMKYRLSFCRKTCGT[Abu]
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PDB ID
1C2U
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 Dissociation constant
0.462 nM
 .
Blocker
 [1]
 Target Info    Kv1.3 Dissociation constant
0.762 nM
 .
Blocker
 [1]
 Target Info    Kv1.1 Dissociation constant
1.045 nM
 .
Blocker
 [1]
 Target Info    Kv1.2-1.1 Dissociation constant
24.2 nM
 .
Blocker
 [1]
 Target Info    Kv1.2 Dissociation constant
56 nM
 .
Blocker
 [1]
 Target Info    KCa3.1 Dissociation constant
981 nM
 .
Blocker
 [1]
References
Ref 1 Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin. Biochemistry. 1999 Nov 2;38(44):14549-58. doi: 10.1021/bi991282m.
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