Peptide Information

General Information of This Peptide

Peptide ID	BTDP008750
Peptide Name	Bgk (W5Y,F6A,Y26F)
3D Structure	Download 2D Sequence Download FASTA 3D Structure Download PDB Source Predict by Alphafold2 ? Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence	VCRDWFKETACRHAKSLGNCRTSQKYRANCAKTLQCC Click to Show/Hide
Mutant Sequence	VCRDYAKETACRHAKSLGNCRTSQKFRANCAKTLQCC Click to Show/Hide
Sequence Length	37
Mass(Da)	4161
Sequence Removed Signal Peptide	VCRDYAKETACRHAKSLGNCRTSQKFRANCAKTCELC Click to Show/Hide
Disulfide Bond	2-30;11-36;20-37
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N.A.

Full List of Activity Data of This Peptide Toxin

Target Name	Activity Data Type	Activity Data	Concentration	Note	Reference
Target Info Kv1.3	.	.	.	Blocker	[1]
Target Info Kv1.2	.	.	.	Blocker	[1]
Target Info Kv1.6	Inhibition constant	0.162 nM	.	Blocker	[1]
Target Info Kv1.1	Inhibition constant	0.215 nM	.	Blocker	[1]
Target Info Kv1.3	Inhibition constant	134.4 nM	.	Blocker	[1]
Target Info Kv1.2	Inhibition constant	289.2 nM	.	Blocker	[1]

References

Ref 1	Characterization of a novel radiolabeled peptide selective for a subpopulation of voltage-gated potassium channels in mammalian brain. J Biol Chem. 2002 Feb 8;277(6):3886-93. doi: 10.1074/jbc.M109886200. Epub 2001 Nov 13.

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