Peptide Information

General Information of This Peptide
Peptide ID
BTDP008595
Peptide Name
Potassium channel toxin alpha-KTx 32.1
Species
Centruroides margaritatus (Central American bark Scorpion)
Uniprot Name
KA321_CENMA
3D Structure
Download
2D Sequence
3D Structure
Source
Predict by Alphafold2
?
Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
KCRECGNTSPSCYFSGNCVNGKCVCPA
   Click to Show/Hide
Sequence Length
27
Mass (Da)
2828
Sequence Removed Signal Peptide
KCRECGNTSPSCYFSGNCVNGKCVCPA
   Click to Show/Hide
Disulfide Bond
5-18;12-25
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Centruroides
Species: Centruroides margaritatus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.2 Dissociation constant
0.96 nM
 .
Blocker
 [1]
 Target Info    Kv1.2 Dissociation constant
0.96 nM
 .
Blocker
 [1]
 Target Info    Kv1.3 Dissociation constant
1.3 nM
 .
Blocker
 [1]
 Target Info    Kv1.3 Dissociation constant
1.3 nM
 .
Blocker
 [1]
 Target Info    Kv1.1 Dissociation constant
400 nM
 .
Blocker
 [1]
 Target Info    KCa3.1 Inhibition rate .
150 nM
Blocker
 [1]
 Target Info    Kv1.5 Inhibition rate .
150 nM
Blocker
 [1]
 Target Info    KCa1.1 Inhibition rate .
150 nM
Blocker
 [1]
 Target Info    Kv11 Inhibition rate .
150 nM
Blocker
 [1]
References
Ref 1 Cm28, a scorpion toxin having a unique primary structure, inhibits KV1.2 and KV1.3 with high affinity. J Gen Physiol. 2022 Aug 1;154(8):e202213146. doi: 10.1085/jgp.202213146. Epub 2022 Jun 14.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.