Peptide Information

General Information of This Peptide
Peptide ID
BTDP008171
Peptide Name
Beta-defensin 3
Symonym
Defensin, beta 3
Species
Mus musculus (Mouse)
Uniprot Name
DEFB3_MOUSE
Alphafold ID
Q9WTL0
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: Q9WTL0
Sequence
KKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK
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Sequence Length
41
Mass (Da)
4618
Sequence Removed Signal Peptide
KKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK
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Disulfide Bond
31-59;38-52;42-60
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Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.2 Inhibition rate
5 %
1 μM
Blocker
 [1]
 Target Info    Kv1.1 Inhibition rate
9 %
1 μM
Blocker
 [1]
 Target Info    Kv1.2 Inhibition rate
9 %
1 μM
Blocker
 [1]
 Target Info    Kv3.2 Inhibition rate
12 %
1 μM
Blocker
 [1]
 Target Info    Kv1.3 Inhibition rate
14 %
1 μM
Blocker
 [1]
 Target Info    Kv1.3 Inhibition rate
15 %
1 μM
Blocker
 [1]
 Target Info    Kv1.1 Inhibition rate
19 %
1 μM
Blocker
 [1]
 Target Info    Kv7.1 Inhibition rate
26 %
1 μM
Blocker
 [1]
 Target Info    Kv1.6 Inhibition rate
31 %
1 μM
Blocker
 [1]
 Target Info    Kv1.6 IC50
600 nM
 .
Blocker
 [1]
 Target Info    Kv7.1 IC50
1.2 μM
 .
Blocker
 [1]
References
Ref 1 Mouse -Defensin 3, A Defensin Inhibitor of Both Its Endogenous and Exogenous Potassium Channels. Molecules. 2018 Jun 20;23(6):1489. doi: 10.3390/molecules23061489.
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