Peptide Information

General Information of This Peptide
Peptide ID
BTDP005710
Peptide Name
GAMMA-ctenitoxin-Pb1a
Symonym
Ctenitoxin-Pb53
Species
Phoneutria boliviensis (Brazilian wandering spider)
Uniprot Name
TX35A_PHOBO
3D Structure
Download
2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
ESNFKIGMAIR
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Sequence Length
11
Mass (Da)
1265
Sequence Removed Signal Peptide
ESNFKIGMAIR
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        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Ctenidae
Genus: Phoneutria
Species: Phoneutria boliviensis
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav Increase rate
105 %
1 μM
 . [1]
 Target Info    Nav Effective concentration 50
212.5 nM
 . . [1]
 Target Info    Nav1.2 IC50
<1.5 μM
 . . [1]
 Target Info    Nav1.4 IC50
<1.5 μM
 . . [1]
 Target Info    Nav1.5 IC50
<1.5 μM
 . . [1]
 Target Info    Nav1.6 IC50
<1.5 μM
 . . [1]
 Target Info    Nav1.3 IC50
1.5 μM
 . . [1]
References
Ref 1 Partial Characterization of Venom from the Colombian Spider Phoneutria Boliviensis (Aranae:Ctenidae). Toxins (Basel). 2015 Jul 31;7(8):2872-87. doi: 10.3390/toxins7082872.
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