Peptide Information

General Information of This Peptide
Peptide ID
BTDP003599
Peptide Name
Alpha-toxin CvIV4
Species
Centruroides vittatus (Striped bark scorpion)
Uniprot Name
SCX4_CENVT
Alphafold ID
F8UWP3
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: F8UWP3
Sequence
MNYFILILVAALLILDVNCKKDGYPVEHSGCKYTCWKNEYCDKVCKDLKGEGGYCYINLT
CWCTGLPDNVPLKTNQRCNGKRK
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Sequence Length
83
Mass (Da)
9488
Signal Sequence
MNYFILILVAALLILDVNC
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Sequence Removed Signal Peptide
KKDGYPVEHSGCKYTCWKNEYCDKVCKDLKGEGGYCYINLTCWCTGLPDNVPLKTNQRCN
GKRK
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Disulfide Bond
31-78;35-55;41-61;45-63
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Centruroides
Species: Centruroides vittatus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.4 Effective concentration 50
530 nM
 . . [1]
 Target Info    Nav1.2 Effective concentration 50
580 nM
 . . [1]
 Target Info    Nav1.3 Effective concentration 50
1.31 μM
 . . [1]
 Target Info    Nav1.7 Effective concentration 50
1.34 μM
 . . [1]
References
Ref 1 Isolation and characterization of CvIV4: a pain inducing -scorpion toxin. PLoS One. 2011;6(8):e23520. doi: 10.1371/journal.pone.0023520. Epub 2011 Aug 24.
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