Target Information

General Information of This Target
Target ID
BTDT10172
Target Name
Oxytocin receptor
Target Bioclass
Receptor
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N.A.
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    Conopressin-T Inhibition constant
108 nM
 [1]
 Toxin Info    Conopressin-S Inhibition constant
175 nM
 [1], [2]
 Toxin Info    Conopressin-T Kact
37 nM
 [1]
 Toxin Info    Conopressin/conophysin, isoform 3 Effective concentration 50
353.73 nM
 [3]
 Toxin Info    Conopressin/conophysin, isoform 3 Effective concentration 50
455.66 nM
 [3]
References
Ref 1 Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides. J Biol Chem. 2008 Mar 14;283(11):7100-8. doi: 10.1074/jbc.M706477200. Epub 2008 Jan 2.
Ref 2 Invertebrate vasopressin/oxytocin homologs. Characterization of peptides from Conus geographus and Conus straitus venoms. J Biol Chem. 1987 Nov 25;262(33):15821-4.
Ref 3 Cone snail analogs of the pituitary hormones oxytocin/vasopressin and their carrier protein neurophysin. Proteomic and transcriptomic identification of conopressins and conophysins. Biochim Biophys Acta Proteins Proteom. 2020 May;1868(5):140391. doi: 10.1016/j.bbapap.2020.140391. Epub 2020 Feb 10.
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