Peptide Information

General Information of This Peptide
Peptide ID
BTDP008716
Peptide Name
Fungal defensin plectasin
Species
Pseudoplectania nigrella (Ebony cup) (Peziza nigrella)
Uniprot Name
DEFPL_PSENR
Alphafold ID
Q53I06
3D Structure
Download
2D Sequence
3D Structure
Source
RSCB PDB: 1ZFU
Sequence
MQFTTILSIGITVFGLLNTGAFAAPQPVPEAYAVSDPEAHPDDFAGMDANQLQKRGFGCN
GPWDEDDMQCHNHCKSIKGYKGGYCAKGGFVCKCY
   Click to Show/Hide
Sequence Length
95
Mass (Da)
10254
Sequence Removed Signal Peptide
GFGCNGPWDEDDMQCHNHCKSIKGYKGGYCAKGGFVCKCY
   Click to Show/Hide
Disulfide Bond
59-85;70-92;74-94
PDB ID
1ZFU , 3E7R , 3E7U , 6K50 , 6K51 , 7O76 , 7OAE , 7OAG
        Click to Show/Hide the Complete Species Lineage
Kingdom: Fungi
Phylum: Ascomycota
Class: Pezizomycetes
Order: Pezizales
Family: Sarcosomataceae
Genus: Pseudoplectania
Species: Pseudoplectania nigrella
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv7 Inhibition rate
3 %
1 μM
Blocker
 [1]
 Target Info    Kv1.2 Inhibition rate
4 %
1 μM
Blocker
 [1]
 Target Info    Kv11 Inhibition rate
4 %
1 μM
Blocker
 [1]
 Target Info    KCa2.3 Inhibition rate
6 %
1 μM
Blocker
 [1]
 Target Info    KCa3.1 Inhibition rate
7 %
1 μM
Blocker
 [1]
 Target Info    Kv1.1 Inhibition rate
16 %
1 μM
Blocker
 [1]
 Target Info    Kv1.3 IC50
2.8 μM
 .
Blocker
 [1]
References
Ref 1 Plectasin, first animal toxin-like fungal defensin blocking potassium channels through recognizing channel pore region. Toxins (Basel). 2015 Jan 5;7(1):34-42. doi: 10.3390/toxins7010034.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.