Peptide Information

General Information of This Peptide
Peptide ID
BTDP008541
Peptide Name
Potassium channel toxin kappa-KTx 2.9
Symonym
Potassium channel-blocking toxin 6
Species
Pandinus imperator (Emperor scorpion)
Uniprot Name
KKX29_PANIM
Alphafold ID
C0HKB3
3D Structure
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2D Sequence
3D Structure
Source
RSCB PDB: 7ZRU
Sequence
VDACYEACMHHHMNSDDCIEACKNPVPP
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Sequence Length
28
Mass (Da)
3131
Sequence Removed Signal Peptide
VDACYEACMHHHMNSDDCIEACKNPVPP
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Disulfide Bond
4-22;8-18
PDB ID
7ZRU
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Scorpionidae
Genus: Pandinus
Species: Pandinus imperator
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.1 Inhibition rate .
100 nM
Blocker
 [1]
 Target Info    Shaker Inhibition rate .
100 nM
Blocker
 [1]
 Target Info    Shab Inhibition rate .
100 nM
Blocker
 [1]
 Target Info    Kv1.4 Inhibition rate .
100 nM
Blocker
 [1]
 Target Info    Kv1.3 Inhibition rate
22 %
100 nM
Blocker
 [1]
 Target Info    Kv1.2 Inhibition rate
31 %
100 nM
Blocker
 [1]
References
Ref 1 Pi5 and Pi6, two undescribed peptides from the venom of the scorpion Pandinus imperator and their effects on K(+)-channels. Toxicon. 2017 Jul;133:136-144. doi: 10.1016/j.toxicon.2017.05.011. Epub 2017 May 11.
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