Peptide Information

General Information of This Peptide
Peptide ID
BTDP008461
Peptide Name
Potassium channel toxin alpha-KTx 13.2
Symonym
OsK-2; OsK2
Species
Orthochirus scrobiculosus (Central Asian scorpion)
Uniprot Name
KA132_ORTSC
Alphafold ID
P83244
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P83244
Sequence
ACGPGCSGSCRQKGDRIKCINGSCHCYP
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Sequence Length
28
Mass (Da)
2901
Sequence Removed Signal Peptide
ACGPGCSGSCRQKGDRIKCINGSCHCYP
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Disulfide Bond
2-19;6-24;10-26
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Orthochirus
Species: Orthochirus scrobiculosus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.2 Dissociation constant
97 nM
 .
Blocker
 [1]
 Target Info    Kv1 Inhibition rate .
250 nM
Blocker
 [1]
 Target Info    Kv1.3 Inhibition rate .
250 nM
Blocker
 [1]
References
Ref 1 OsK2, a new selective inhibitor of Kv1.2 potassium channels purified from the venom of the scorpion Orthochirus scrobiculosus. Biochem Biophys Res Commun. 2001 Sep 7;286(5):841-7. doi: 10.1006/bbrc.2001.5492.
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