Peptide Information

General Information of This Peptide

Peptide ID	BTDP001034
Peptide Name	Anuroctoxin (N17A)
Symonym	Anuroctoxin (N17A)
3D Structure	Download 2D Sequence Download FASTA 3D Structure Download PDB Source Predict by Alphafold2 ? Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence	QKECTGPQHCTNFCRKNKCTHGKCMNRKCKCTNCK Click to Show/Hide
Mutant Sequence	QKECTGPQHCTNFCRKAKCTHGKCMNRKCKCFNCK Click to Show/Hide
Sequence Length	35
Mass(Da)	4040
Sequence Removed Signal Peptide	QKECTGPQHCTNFCRKAKCTHGKCMNRKCKCFNCK Click to Show/Hide
*Click to Show/Hide the Complete Species Lineage*
N.A.

Full List of Activity Data of This Peptide Toxin

Target Name	Activity Data Type	Activity Data	Concentration	Note	Reference
Target Info Kv1.3	Dissociation constant	1.2 nM	.	Blocker	[1]
Target Info Kv1.2	Dissociation constant	20 nM	.	Blocker	[1]
Target Info KCa3.1	Inhibition rate	.	100 nM	Blocker	[1]
Target Info Kv1.1	Inhibition rate	.	100 nM	Blocker	[1]

References

Ref 1	An engineered scorpion toxin analogue with improved Kv1.3 selectivity displays reduced conformational flexibility. Sci Rep. 2015 Dec 22;5:18397. doi: 10.1038/srep18397.

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