Target Information

General Information of This Target
Target ID
BTDT10173
Target Name
P2X purinoceptor 7
Target Bioclass
Receptor
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N.A.
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    PI-stichotoxin-Hmg3d Dissociation constant
43.3 μM
 [1]
 Toxin Info    PI-stichotoxin-Hcr2j Dissociation constant
45.5 μM
 [1], [2]
References
Ref 1 Kunitz-Type Peptides from Sea Anemones Protect Neuronal Cells against Parkinson's Disease Inductors via Inhibition of ROS Production and ATP-Induced P2X7 Receptor Activation. Int J Mol Sci. 2022 May 4;23(9):5115. doi: 10.3390/ijms23095115.
Ref 2 A new multigene HCIQ subfamily from the sea anemone Heteractis crispa encodes Kunitz-peptides exhibiting neuroprotective activity against 6-hydroxydopamine. Sci Rep. 2020 Mar 6;10(1):4205. doi: 10.1038/s41598-020-61034-x.
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