Target Information

General Information of This Target
Target ID
BTDT10159
Target Name
Nicotinic acetylcholine receptor (nAChR) alpha-7
Target Bioclass
Receptor
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N.A.
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    Venom peptide Sh42 Effect . [1]
 Toxin Info    Alpha-conotoxin Pu14.1 Inhibition rate . [2]
 Toxin Info    Alpha-conotoxin Vc1.2 IC50
637 nM
 [3]
References
Ref 1 Isolation and characterization of FMRFamide-like peptides in the venoms of solitary sphecid wasps. Peptides. 2021 Aug;142:170575. doi: 10.1016/j.peptides.2021.170575. Epub 2021 May 20.
Ref 2 A new subfamily of conotoxins belonging to the A-superfamily. Peptides. 2010 Nov;31(11):2009-16. doi: 10.1016/j.peptides.2010.07.011. Epub 2010 Aug 4.
Ref 3 Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function?. J Biol Chem. 2011 Jun 24;286(25):22546-57. doi: 10.1074/jbc.M110.217703. Epub 2011 Apr 19.
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