Peptide Information

General Information of This Peptide
Peptide ID
BTDP002952
Peptide Name
Alpha-conotoxin Pu14.1
Species
Conus pulicarius (Flea-bitten cone)
Uniprot Name
CAE1_CONPL
Alphafold ID
C6ZJQ2
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: C6ZJQ2
Sequence
MGMRMMFAVFLLVVLATTVVSFNSDRASDGRNAAANVKASDLMARVLEKDCPPHPVPGMH
KCVCLKTCR
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Sequence Length
69
Mass (Da)
7510
Signal Sequence
MGMRMMFAVFLLVVLATTVVS
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Sequence Removed Signal Peptide
FNSDRASDGRNAAANVKASDLMARVLEKDCPPHPVPGMHKCVCLKTCR
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Disulfide Bond
51-64;62-68
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus pulicarius
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-3-beta-4 Inhibition rate .
10 μM
 . [1]
 Target Info    nAChR alpha-4-beta-2 Inhibition rate .
10 μM
 . [1]
 Target Info    nAChR alpha-4-beta-4 Inhibition rate .
10 μM
 . [1]
 Target Info    nAChR alpha-6/alpha-3-beta-4 Inhibition rate .
10 μM
 . [1]
 Target Info    nAChR alpha-7 Inhibition rate .
1 μM
 . [1]
References
Ref 1 A new subfamily of conotoxins belonging to the A-superfamily. Peptides. 2010 Nov;31(11):2009-16. doi: 10.1016/j.peptides.2010.07.011. Epub 2010 Aug 4.
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