Target Information

General Information of This Target
Target ID
BTDT10129
Target Name
Nicotinic acetylcholine receptor (nAChR) alpha-3/beta-4
Target Bioclass
Receptor
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N.A.
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    Alpha-elapitoxin-Dpp2d Inhibition rate . [1]
 Toxin Info    Alpha/kappa-conotoxin pl14a IC50
8.7 μM
 [2]
References
Ref 1 Isolation and structural and pharmacological characterization of -elapitoxin-Dpp2d, an amidated three finger toxin from black mamba venom. Biochemistry. 2014 Jun 17;53(23):3758-66. doi: 10.1021/bi5004475. Epub 2014 Jun 5.
Ref 2 A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins. Biochemistry. 2006 Jul 11;45(27):8331-40. doi: 10.1021/bi060263r.
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