Target Information

General Information of This Target
Target ID
BTDT10088
Target Name
Nicotinic acetylcholine receptor (muscle)
Target Bioclass
Receptor
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N.A.
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    Alpha-elapitoxin-Bc2a IC50
30 nM
 [1]
 Toxin Info    Alpha-elapitoxin-Dpp2d IC50
114 nM
 [2]
References
Ref 1 Novel long-chain neurotoxins from Bungarus candidus distinguish the two binding sites in muscle-type nicotinic acetylcholine receptors. Biochem J. 2019 Apr 26;476(8):1285-1302. doi: 10.1042/BCJ20180909.
Ref 2 Isolation and structural and pharmacological characterization of -elapitoxin-Dpp2d, an amidated three finger toxin from black mamba venom. Biochemistry. 2014 Jun 17;53(23):3758-66. doi: 10.1021/bi5004475. Epub 2014 Jun 5.
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