Peptide Information

General Information of This Peptide
Peptide ID
BTDP001839
Peptide Name
Alpha-elapitoxin-Bc2a
Symonym
Alpha-delta-Bgt-1; Alpha/delta-bungarotoxin-1
Species
Bungarus candidus (Malayan krait)
Uniprot Name
3L21_BUNCA
Alphafold ID
A1IVR8
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: A1IVR8
Sequence
YTLLCYKTPSPINAETCPPGENLCYTKMWCDAWCSSRGKVIELGCAATCPSKKPYEEVTC
CSTDKCNPHPKQRPG
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Sequence Length
75
Mass (Da)
8306
Sequence Removed Signal Peptide
YTLLCYKTPSPINAETCPPGENLCYTKMWCDAWCSSRGKVIELGCAATCPSKKPYEEVTC
CSTDKCNPHPKQRPG
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Disulfide Bond
5-24;17-45;30-34;49-60;61-66
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Elapidae
Genus: Bungarus
Species: Bungarus candidus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR muscular IC50
30 nM
 . . [1]
 Target Info    nAChR alpha-3-beta-2 IC50
2.9 μM
 . . [1]
References
Ref 1 Novel long-chain neurotoxins from Bungarus candidus distinguish the two binding sites in muscle-type nicotinic acetylcholine receptors. Biochem J. 2019 Apr 26;476(8):1285-1302. doi: 10.1042/BCJ20180909.
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