Target Information

General Information of This Target
Target ID
BTDT10037
Target Name
Coagulation factor XI
Target Bioclass
Coagulation factor
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N.A.
Toxin Information Related to This Target
                           Toxin Name Activity Data Type Activity Data Reference
 Toxin Info    Kunitz-type serine protease inhibitor DrKIn-II Inhibition constant
6 nM
 [1], [2]
 Toxin Info    Kunitz-type serine protease inhibitor DrKIn-I Inhibition rate
40 %
 [1]
References
Ref 1 A novel heparin-dependent inhibitor of activated protein C that potentiates consumptive coagulopathy in Russell's viper envenomation. J Biol Chem. 2012 May 4;287(19):15739-48. doi: 10.1074/jbc.M111.323063. Epub 2012 Mar 13.
Ref 2 Functional characterization of a slow and tight-binding inhibitor of plasmin isolated from Russell's viper venom. Biochim Biophys Acta. 2014 Jan;1840(1):153-9. doi: 10.1016/j.bbagen.2013.08.019. Epub 2013 Aug 30.
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