Peptide Information

General Information of This Peptide
Peptide ID
BTDP008709
Peptide Name
Neurotoxin lambda-MeuTx
Symonym
Calcium channel toxin-like peptide-1
Species
Mesobuthus eupeus (Lesser Asian scorpion) (Buthus eupeus)
Uniprot Name
CLML_MESEU
Alphafold ID
P86399
3D Structure
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2D Sequence
3D Structure
Source
RSCB PDB: 8F2F
Sequence
MSTFIVVFLLLTAILCHAEHAIDETARGCNRLNKKCNSDADCCRYGERCISTGVNYYCRP
DFGP
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Sequence Length
64
Mass (Da)
7177
Signal Sequence
MSTFIVVFLLLTAILCHA
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Sequence Removed Signal Peptide
EHAIDETARGCNRLNKKCNSDADCCRYGERCISTGVNYYCRPDFGP
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Disulfide Bond
29-43;36-49;42-58
PDB ID
8F2F
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Mesobuthus
Species: Mesobuthus eupeus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1 Inhibition rate .
100 μM
Blocker
 [1]
 Target Info    Kv1.2 Inhibition rate .
100 μM
Blocker
 [1]
 Target Info    Kv1.3 Inhibition rate .
100 μM
Blocker
 [1]
 Target Info    Kv1.4 Inhibition rate .
100 μM
Blocker
 [1]
 Target Info    Shaker IC50
12.3 μM
 .
Blocker
 [1]
References
Ref 1 Functional evolution of scorpion venom peptides with an inhibitor cystine knot fold. Biosci Rep. 2013 Jun 27;33(3):e00047. doi: 10.1042/BSR20130052.
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