Peptide Information

General Information of This Peptide
Peptide ID
BTDP008691
Peptide Name
Contryphan-Vn
Species
Conus ventricosus (Mediterranean cone)
Uniprot Name
COW_CONVE
3D Structure
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2D Sequence
3D Structure
Source
RSCB PDB: 1NXN
Sequence
GDCPWKPWC
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Sequence Length
9
Mass (Da)
1091
Sequence Removed Signal Peptide
GDCPWKPWC
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Disulfide Bond
39
PDB ID
1NXN
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus ventricosus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.1 Inhibition rate .
600 μM
 . [1], [2], [3]
 Target Info    Kv1.2 Inhibition rate .
600 μM
 . [1], [2], [3]
References
Ref 1 Contryphan-Vn: a novel peptide from the venom of the Mediterranean snail Conus ventricosus. Biochem Biophys Res Commun. 2001 Nov 9;288(4):908-13. doi: 10.1006/bbrc.2001.5833.
Ref 2 Contryphan-Vn: a modulator of Ca2+-dependent K+ channels. Biochem Biophys Res Commun. 2003 Mar 28;303(1):238-46. doi: 10.1016/s0006-291x(03)00331-0.
Ref 3 Solution structure of the cyclic peptide contryphan-Vn, a Ca2+-dependent K+ channel modulator. Biopolymers. 2004 Jun 15;74(3):189-98. doi: 10.1002/bip.20025.
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