Peptide Information

General Information of This Peptide
Peptide ID
BTDP008620
Peptide Name
Voltage sensor toxin 3
Symonym
Beta/kappa-theraphotoxin-Gr4a
Species
Grammostola rosea (Chilean rose tarantula) (Grammostola spatulata)
Uniprot Name
VSTX3_GRARO
Alphafold ID
P0C2P5
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0C2P5
Sequence
DCLGWFKGCDPDNDKCCEGYKCNRRDKWCKYKLW
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Sequence Length
34
Mass (Da)
4178
Sequence Removed Signal Peptide
DCLGWFKGCDPDNDKCCEGYKCNRRDKWCKYKLW
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Disulfide Bond
2-17;9-22;16-29
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Theraphosidae
Genus: Grammostola
Species: Grammostola rosea
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    KvAP . . .
Modifier
 [1]
 Target Info    Nav1.3 IC50
190 nM
 .
Modifier
 [1]
 Target Info    Nav1.3 IC50
210 nM
 .
Modifier
 [1]
 Target Info    Nav1.8 IC50
290 nM
 .
Modifier
 [1]
 Target Info    Nav1.7 IC50
430 nM
 .
Modifier
 [1]
 Target Info    Nav1.8 IC50
770 nM
 .
Modifier
 [1]
References
Ref 1 Localization of the voltage-sensor toxin receptor on KvAP. Biochemistry. 2004 Aug 10;43(31):10071-9. doi: 10.1021/bi049463y.
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