Peptide Information

General Information of This Peptide
Peptide ID
BTDP008582
Peptide Name
Conopeptide Y-Fe1
Symonym
CPY-Fe1
Species
Conus ferrugineus (Cone snail)
Uniprot Name
CPY1_CONFR
Alphafold ID
B3SVF1
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: B3SVF1
Sequence
MSKLGVVLFVFLLLLPLAAPQPVGDQPADQPADRNAEARGTYLYPFSYYRLWRYFTRFLH
KQPYYYVHI
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Sequence Length
69
Mass (Da)
8184
Sequence Removed Signal Peptide
GTYLYPFSYYRLWRYFTRFLHKQPYYYVHI
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus ferrugineus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.2 Inhibition rate .
30 μM
 . [1]
 Target Info    Kv1.3 Inhibition rate .
50 μM
 . [1]
 Target Info    Kv1.4 Inhibition rate .
50 μM
 . [1]
 Target Info    Kv1.5 Inhibition rate .
50 μM
 . [1]
 Target Info    Kv1.2 IC50
>30 μM
 . . [1]
 Target Info    Kv1.3 IC50
>50 μM
 . . [1]
 Target Info    Kv1.4 IC50
>50 μM
 . . [1]
 Target Info    Kv1.5 IC50
>50 μM
 . . [1]
 Target Info    Kv1.6 IC50
8.8 μM
 . . [1]
 Target Info    Kv1.6 IC50
8.8 μM
 . . [1]
References
Ref 1 Tyrosine-rich conopeptides affect voltage-gated K+ channels. J Biol Chem. 2008 Aug 22;283(34):23026-32. doi: 10.1074/jbc.M800084200. Epub 2008 May 27.
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