Peptide Information

General Information of This Peptide
Peptide ID
BTDP006233
Peptide Name
Omega-filistatoxin-Kh1a
Symonym
Toxin DW13.3
Species
Kukulcania hibernalis (Southern house spider) (Filistata hibernalis)
Uniprot Name
TX13_KUKHI
Alphafold ID
P60979
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: P60979
Sequence
AECLMIGDTSCVPRLGRRCCYGAWCYCDQQLSCRRVGRKRECGWVEVNCKCGWSWSQRID
DWRADYSCKCPEDQ
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Sequence Length
74
Mass (Da)
8680
Sequence Removed Signal Peptide
AECLMIGDTSCVPRLGRRCCYGAWCYCDQQLSCRRVGRKRECGWVEVNCKCGWSWSQRID
DWRADYSCKCPEDQ
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        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Filistatidae
Genus: Kukulcania
Species: Kukulcania hibernalis
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Cav2.2 IC50
2.3 nM
 . . [1]
 Target Info    Cav2.1 IC50
4.3 nM
 . . [1]
 Target Info    Cav2.2 IC50
14.4 nM
 . . [1]
 Target Info    Cav1.2 IC50
26.8 nM
 . . [1]
 Target Info    Cav2.3 IC50
96.4 nM
 . . [1]
References
Ref 1 Inhibition of neuronal calcium channels by a novel peptide spider toxin, DW13.3. Mol Pharmacol. 1998 Aug;54(2):407-18. doi: 10.1124/mol.54.2.407.
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