Peptide Information

General Information of This Peptide
Peptide ID
BTDP005695
Peptide Name
Omega-theraphotoxin-Avsp1a
Symonym
Omega-TRTX-Avsp1a
Species
Avicularia sp. (Arboreal tarantula)
Uniprot Name
NTA_AVISX
3D Structure
Download
2D Sequence
3D Structure
Source
RSCB PDB: 7LVN
Sequence
GDCHKFLGWCRGEPDPCCEHLSCSRKHGWCVWDWTV
   Click to Show/Hide
Sequence Length
36
Mass (Da)
4235
Sequence Removed Signal Peptide
GDCHKFLGWCRGEPDPCCEHLSCSRKHGWCVWDWTV
   Click to Show/Hide
Disulfide Bond
3-18;10-23;17-30
PDB ID
7LVN
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Theraphosidae
Genus: Avicularia
Species: Avicularia sp.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Cav2.2 IC50
>25 μM
 . . [1]
 Target Info    Cav3.3 IC50
4.32 μM
 . . [1]
 Target Info    Cav3.1 IC50
5.06 μM
 . . [1]
References
Ref 1 The Tarantula Toxin -Avsp1a Specifically Inhibits Human Ca(V)3.1 and Ca(V)3.3 via the Extracellular S3-S4 Loop of the Domain 1 Voltage-Sensor. Biomedicines. 2022 May 4;10(5):1066. doi: 10.3390/biomedicines10051066.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.