General Information of This Peptide
Peptide ID
BTDP005449
Peptide Name
Elevenin
Species
Conus ebraeus (Hebrew cone)
Uniprot Name
CELE_CONEA
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
MAPSQKALLVLVLSMLLTASDSRARRIDCTRFVYAPICRGVAAKRGGDSLSVGASTELDD
ALTDPFLRSEEPREEDTEKKWRELSRLSRVLQILLSHPTGETEQLDRLLTL
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Sequence Length
111
Mass (Da)
12383
Signal Sequence
MAPSQKALLVLVLSMLLTASDSRA
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Sequence Removed Signal Peptide
RRIDCTRFVYAPICRGVAAKRGGDSLSVGASTELDDALTDPFLRSEEPREEDTEKKWREL
SRLSRVLQILLSHPTGETEQLDRLLTL
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Disulfide Bond
29-38
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus ebraeus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-7 Effect .
1 μM
. [1]
 Target Info    nAChR alpha-1-beta-1-epsilon-delta-epsilon Effect .
1 μM
. [1]
 Target Info    nAChR alpha-3-beta-2 Effect .
1 μM
. [1]
 Target Info    nAChR alpha-3-beta-4 Effect .
1 μM
. [1]
 Target Info    nAChR alpha-4-beta-2 Effect .
1 μM
. [1]
 Target Info    nAChR alpha-9-alpha-10 Effect .
1 μM
. [1]
References
Ref 1 Comparative Venomics of the Cryptic Cone Snail Species Virroconus ebraeus and Virroconus judaeus. Mar Drugs. 2022 Feb 17;20(2):149. doi: 10.3390/md20020149.
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