Peptide Information

General Information of This Peptide
Peptide ID
BTDP005448
Peptide Name
Elevenin
Symonym
Conoporin
Species
Conus ammiralis (Admiral cone)
Uniprot Name
CELE_CONAJ
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
MALSQKALLVLVLSMLLTASDSWARRINCKVFVYAPICRGVAAKRGGDSLSVGGSAELDD
TLTDPFLKSEEPKEWRELTRLSRVLQTFLSHPTGEMEQHD
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Sequence Length
100
Mass (Da)
11091
Signal Sequence
MALSQKALLVLVLSMLLTASDSWA
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Sequence Removed Signal Peptide
RRINCKVFVYAPICRGVAAKRGGDSLSVGGSAELDDTLTDPFLKSEEPKEWRELTRLSRV
LQTFLSHPTGEMEQHD
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Disulfide Bond
29-38
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus ammiralis
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-7 Effect .
1 μM
 . [1]
 Target Info    nAChR alpha-1-beta-1-epsilon-delta-epsilon Effect .
1 μM
 . [1]
 Target Info    nAChR alpha-3-beta-2 Effect .
1 μM
 . [1]
 Target Info    nAChR alpha-3-beta-4 Effect .
1 μM
 . [1]
 Target Info    nAChR alpha-4-beta-2 Effect .
1 μM
 . [1]
 Target Info    nAChR alpha-9-alpha-10 Effect .
1 μM
 . [1]
References
Ref 1 A Combined Transcriptomics and Proteomics Approach Reveals the Differences in the Predatory and Defensive Venoms of the Molluscivorous Cone Snail Cylinder ammiralis (Caenogastropoda: Conidae). Toxins (Basel). 2021 Sep 10;13(9):642. doi: 10.3390/toxins13090642.
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