Peptide Information

General Information of This Peptide

Peptide ID	BTDP005407
Peptide Name	Nemertide alpha-6
Species	Lineus sanguineus (Ribbon worm)
Uniprot Name	NEMA6_LINSA
3D Structure	Download 2D Sequence Download FASTA 3D Structure Download PDB Source Predict by Alphafold2 ? Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence	GCIKTGSFCTLSKGCCTKNCGWNFHCNPPNQ Click to Show/Hide
Sequence Length	31
Mass (Da)	3350
Sequence Removed Signal Peptide	GCIKTGSFCTLSKGCCTKNCGWNFHCNPPNQ Click to Show/Hide
Disulfide Bond	2-16;9-20;15-26
*Click to Show/Hide the Complete Species Lineage*
Kingdom: Metazoa Phylum: Nemertea Class: Pilidiophora Order: Heteronemertea Family: Lineidae Genus: Lineus Species: Lineus sanguineus

Full List of Activity Data of This Peptide Toxin

Target Name	Activity Data Type	Activity Data	Concentration	Note	Reference
Target Info BgNav1	Effective concentration 50	2.6 nM	.	.	[1], [2]
Target Info Nav1.2	Effective concentration 50	7.9 nM	.	.	[1], [2]
Target Info Nav1.3	Effective concentration 50	24.3 nM	.	.	[1], [2]
Target Info Nav1.9	Effective concentration 50	36.3 nM	.	.	[1], [2]
Target Info Nav1.5	Effective concentration 50	46.4 nM	.	.	[1], [2]
Target Info Nav1.1	Effective concentration 50	97.2 nM	.	.	[1], [2]
Target Info Nav1.4	Effective concentration 50	105.6 nM	.	.	[1], [2]
Target Info Nav1.6	Effective concentration 50	215.2 nM	.	.	[1], [2]

References

Ref 1	Peptide ion channel toxins from the bootlace worm, the longest animal on Earth. Sci Rep. 2018 Mar 22;8(1):4596. doi: 10.1038/s41598-018-22305-w.
Ref 2	Functional Characterization of the Nemertide Family of Peptide Toxins. J Nat Prod. 2021 Aug 27;84(8):2121-2128. doi: 10.1021/acs.jnatprod.1c00104. Epub 2021 Aug 16.

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