Peptide Information

General Information of This Peptide
Peptide ID
BTDP004452
Peptide Name
Delta-conotoxin-like CnVIB
Symonym
Delta-CnVIB
Species
Conus consors (Singed cone)
Uniprot Name
O16B_CONCN
Alphafold ID
P0CC13
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0CC13
Sequence
DECFSPGTFCGTKPGLCCSARCFSFFCISLEF
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Sequence Length
32
Mass (Da)
3504
Sequence Removed Signal Peptide
DECFSPGTFCGTKPGLCCSARCFSFFCISLEF
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Disulfide Bond
3-18;10-22;17-27
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus consors
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.4 Effective concentration 50
2.3 μM
 . . [1], [2]
 Target Info    Nav1.6 Effective concentration 50
2.3 μM
 . . [1], [2]
References
Ref 1 -Conotoxins synthesized using an acid-cleavable solubility tag approach reveal key structural determinants for NaV subtype selectivity. J Biol Chem. 2014 Dec 19;289(51):35341-50. doi: 10.1074/jbc.M114.610436. Epub 2014 Oct 28.
Ref 2 Comparative proteomic study of the venom of the piscivorous cone snail Conus consors. J Proteomics. 2009 Mar 6;72(2):210-8. doi: 10.1016/j.jprot.2009.01.019. Epub 2009 Jan 23.
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