Peptide Information

General Information of This Peptide
Peptide ID
BTDP002676
Peptide Name
Alpha-mammal toxin AnCra1
Species
Androctonus crassicauda (Arabian fat-tailed scorpion)
Uniprot Name
SCX9_ANDCR
Alphafold ID
C0HLG5
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: C0HLG5
Sequence
LKDGYIVDDVNCTYFCGRNAYCNEECIKLKGESGYCQWASPYGNACYCYKLPDHVRTKGP
GRCN
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Sequence Length
64
Mass (Da)
7255
Sequence Removed Signal Peptide
LKDGYIVDDVNCTYFCGRNAYCNEECIKLKGESGYCQWASPYGNACYCYKLPDHVRTKGP
GRCN
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Disulfide Bond
12-63;16-36;22-46;26-48
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Androctonus
Species: Androctonus crassicauda
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 Effective concentration 50
136.7 nM
 . . [1]
 Target Info    Nav1.5 Effective concentration 50
31.9 μM
 . . [1]
References
Ref 1 Expression and purification of recombinant alpha-toxin AnCra1 from the scorpion Androctonus crassicauda and its functional characterization on mammalian sodium channels. Mol Biol Rep. 2021 Sep;48(9):6303-6312. doi: 10.1007/s11033-021-06624-2. Epub 2021 Aug 11.
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