Peptide Information

General Information of This Peptide
Peptide ID
BTDP001163
Peptide Name
PTx2-3258
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
YCQKWMWTCDSERKCCEGMVCRLWCKKKLW
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Mutant Sequence
HCQKWNQTCDKDRKCCEGFRCRLWCRKELL
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Sequence Length
30
Mass(Da)
3787
Sequence Removed Signal Peptide
HCQKWNQTCDKDRKCCEGFRCRLWCRKELL
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Disulfide Bond
2-16;9-21;15-25
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
3.8 nM
 . . [1]
 Target Info    Nav1.6 IC50
382 nM
 . . [1]
 Target Info    Kv11/ERG IC50
1.861 μM
 . . [1]
 Target Info    Nav1.2 IC50
3.399 μM
 . . [1]
 Target Info    Nav1.1 IC50
5.013 μM
 . . [1]
 Target Info    Nav1.4 IC50
8.877 μM
 . . [1]
 Target Info    Nav1.3 IC50
14.093 μM
 . . [1]
 Target Info    Nav1.5 IC50
38.315 μM
 . . [1]
 Target Info    Nav1.8 IC50
43.079 μM
 . . [1]
 Target Info    Nav1.9 IC50
59.443 μM
 . . [1]
References
Ref 1 The alchemy of culture: intoxicants in society. BMJ. 1998 Nov 28;317(7171):1532B. doi: 10.1136/bmj.317.7171.1532b.
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