Peptide Information

General Information of This Peptide
Peptide ID
BTDP001161
Peptide Name
PTx2-3127
3D Structure
Download
2D Sequence
3D Structure
Source
Predict by Alphafold2
?
Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
YCQKWMWTCDSERKCCEGMVCRLWCKKKLW
   Click to Show/Hide
Mutant Sequence
QCQKWMQTCDKDRKCCEGFRCRLWCRKELL
   Click to Show/Hide
Sequence Length
30
Mass(Da)
3580
Sequence Removed Signal Peptide
QCQKWMQTCDKDRKCCEGFRCRLWCRKELL
   Click to Show/Hide
Disulfide Bond
2-16;9-21;15-25
        Click to Show/Hide the Complete Species Lineage
N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
6.9 nM
 . . [1]
 Target Info    Nav1.6 IC50
608 nM
 . . [1]
 Target Info    Nav1.9 IC50
>150 μM
 . . [1]
 Target Info    Nav1.8 IC50
>150 μM
 . . [1]
 Target Info    Kv11/ERG IC50
1.889 μM
 . . [1]
 Target Info    Nav1.2 IC50
5.04 μM
 . . [1]
 Target Info    Nav1.4 IC50
11.53 μM
 . . [1]
 Target Info    Nav1.1 IC50
16.97 μM
 . . [1]
 Target Info    Nav1.3 IC50
20.04 μM
 . . [1]
 Target Info    Nav1.5 IC50
137.09 μM
 . . [1]
References
Ref 1 Computational design of peptides to target Na(V)1.7 channel with high potency and selectivity for the treatment of pain. Elife. 2022 Dec 28;11:e81727. doi: 10.7554/eLife.81727.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.