Peptide Information

General Information of This Peptide
Peptide ID
BTDP001132
Peptide Name
Potassium channel toxin alpha-KTx (N30P)
Symonym
Potassium channel toxin alpha-KTx (N30P)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Mutant Sequence
VDFPNKGGKCDRKECRKTCKKLNYRGKCFNNYCRCFP
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Sequence Length
37
Mass(Da)
4414
Sequence Removed Signal Peptide
VDFPNKGGKCDRKECRKTCKKLNYRGKCFNNYCRCFP
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Shaker-IR Inhibition rate
10 %
100 μM
Blocker
 [1]
 Target Info    Kv1.2 Inhibition rate
29 %
100 μM
Blocker
 [1]
 Target Info    Kv1 Inhibition rate
38 %
100 μM
Blocker
 [1]
 Target Info    Kv1.3 Inhibition rate
42 %
100 μM
Blocker
 [1]
References
Ref 1 A single-point mutation enhances dual functionality of a scorpion toxin. Comp Biochem Physiol C Toxicol Pharmacol. 2016 Jan;179:72-8. doi: 10.1016/j.cbpc.2015.09.002. Epub 2015 Sep 7.
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