Peptide Information

General Information of This Peptide
Peptide ID
BTDP001119
Peptide Name
Kappa-hefutoxin 3 (K20E)
Symonym
Kappa-hefutoxin 3 (K20E)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
CYRNCWREGNDEETCKERC
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Mutant Sequence
GFGCYRSCWKAGHDEETCKAECS
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Sequence Length
23
Mass(Da)
2564
Sequence Removed Signal Peptide
GFGCYRSCWKAGHDEETCKAECS
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.2 IC50
36.9 μM
 .
Blocker
 [1]
 Target Info    Kv1.3 IC50
115.7 μM
 .
Blocker
 [1]
References
Ref 1 Assignment of voltage-gated potassium channel blocking activity to kappa-KTx1.3, a non-toxic homologue of kappa-hefutoxin-1, from Heterometrus spinifer venom. Biochem Pharmacol. 2005 Feb 15;69(4):669-78. doi: 10.1016/j.bcp.2004.10.018. Epub 2004 Dec 29.
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