Peptide Information

General Information of This Peptide
Peptide ID
BTDP000879
Peptide Name
CboK2 (D2N,K6R,R7K,R8K,N18G,A19R)
Symonym
CboK2 (D2N,K6R,R7K,R8K,N18G,A19R)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Mutant Sequence
AGCGSCNKDCRKKGYRSGKCINGRCKCYP
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Sequence Length
29
Mass(Da)
3151
Sequence Removed Signal Peptide
AGCGSCNKDCRKKGYRSGKCINGRCKCYP
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv3.2 Inhibition rate .
100 μM
Blocker
 [1]
 Target Info    Kv4.1 Inhibition rate .
100 μM
Blocker
 [1]
 Target Info    Kv1.1 Inhibition rate
4 %
100 μM
Blocker
 [1]
 Target Info    Kv1.3 Inhibition rate
9 %
100 μM
Blocker
 [1]
References
Ref 1 ImKTx96, a peptide blocker of the Kv1.2 ion channel from the venom of the scorpion Isometrus maculates. Peptides. 2020 Jan;123:170172. doi: 10.1016/j.peptides.2019.170172. Epub 2019 Oct 15.
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