Peptide Information

General Information of This Peptide
Peptide ID
BTDP000765
Peptide Name
Potassium channel toxin AbeTx1 (R,K6A)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
RCKTCSKGRCRPKPNCG
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Mutant Sequence
RCKTCSAGRCRPKPNCG
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Sequence Length
17
Mass(Da)
1833
Sequence Removed Signal Peptide
RCKTCSAGRCRPKPNCG
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.6 IC50
852 nM
 .
Blocker
 [1]
 Target Info    Kv1 IC50
17.759 μM
 .
Blocker
 [1]
References
Ref 1 AbeTx1 Is a Novel Sea Anemone Toxin with a Dual Mechanism of Action on Shaker-Type K? Channels Activation. Mar Drugs. 2018 Oct 1;16(10):360. doi: 10.3390/md16100360.
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