Peptide Information

General Information of This Peptide
Peptide ID
BTDP000763
Peptide Name
Potassium channel toxin AbeTx1 (R,K12A)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
RCKTCSKGRCRPKPNCG
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Mutant Sequence
RCKTCSKGRCRPAPNCG
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Sequence Length
17
Mass(Da)
1833
Sequence Removed Signal Peptide
RCKTCSKGRCRPAPNCG
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        Click to Show/Hide the Complete Species Lineage
N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.6 IC50
1.077 μM
 .
Blocker
 [1]
 Target Info    Kv1 IC50
4.548 μM
 .
Blocker
 [1]
References
Ref 1 AbeTx1 Is a Novel Sea Anemone Toxin with a Dual Mechanism of Action on Shaker-Type K? Channels Activation. Mar Drugs. 2018 Oct 1;16(10):360. doi: 10.3390/md16100360.
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