Peptide Information

General Information of This Peptide
Peptide ID
BTDP000497
Peptide Name
Potassium channel toxin ShK (R11Q)
Symonym
Potassium channel toxin ShK (R11Q)
3D Structure
Original Sequence
RSCIDTIPKSRCTAFKCKHSMKYRLSFCRKTCGTC
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Mutant Sequence
RSCIDTIPKSQCTAFQCKHSMKYRLSFCRKTCGTC
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Sequence Length
35
Mass(Da)
4027
Sequence Removed Signal Peptide
RSCIDTIPKSQCTAFQCKHSMKYRLSFCRKTCGTC
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 IC50
5.586 nM
 .
Blocker
 [1]
 Target Info    Kv1 IC50
18 nM
 .
Blocker
 [1]
References
Ref 1 Identification of three separate binding sites on SHK toxin, a potent inhibitor of voltage-dependent potassium channels in human T-lymphocytes and rat brain. Biochem Biophys Res Commun. 1996 Feb 27;219(3):696-701. doi: 10.1006/bbrc.1996.0297.
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