Peptide Information

General Information of This Peptide
Peptide ID
BTDP000466
Peptide Name
Potassium channel toxin ShK (K9Q)
Symonym
Potassium channel toxin ShK (K9Q)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
RSCIDTIPKSRCTAFKCKHSMKYRLSFCRKTCGTC
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Mutant Sequence
RSCIDTIPQSRCTAFQCKHSMKYRLSFCRKTCGTC
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Sequence Length
35
Mass(Da)
4055
Sequence Removed Signal Peptide
RSCIDTIPQSRCTAFQCKHSMKYRLSFCRKTCGTC
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 IC50
1.27 nM
 .
Blocker
 [1]
 Target Info    Kv1 IC50
6 nM
 .
Blocker
 [1]
References
Ref 1 Identification of three separate binding sites on SHK toxin, a potent inhibitor of voltage-dependent potassium channels in human T-lymphocytes and rat brain. Biochem Biophys Res Commun. 1996 Feb 27;219(3):696-701. doi: 10.1006/bbrc.1996.0297.
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